Supercritical C0₂

SCCO₂ refers to carbon dioxide that is in a fluid state when both its temperature and pressure are equal to or greater than the critical point. Carbon dioxide usually behaves as a gas under standard temperature and pressure conditions (STP), or as a solid when frozen (dry ice). When the temperature and pressure are increased from STP to be at or above the critical point (31.1°C, 74 atm) of carbon dioxide, it develops properties midway between a gas and a liquid. At this point, it is referred to as a supercritical fluid. SCCO₂ has become a popular commercial and industrial solvent because of its low toxicity and low environmental impact.

Supercritical CO₂ technology uses the solvent properties of carbon dioxide gas compressed to its critical point (the point at which the liquid and vapor phases become indistinguishable), defined by pressure (Pc= 1,099 psi) and temperature (Tc=31.1°C). The critical region is characterized by an ability to control solvent power with only minor changes in pressure and temperature. The inherent properties of SCCO₂, such as density and solvency, gas like viscosity, diffusivity, compressibility, and very low surface tension, facilitate penetration to the interior of bone tissue thereby allowing inactivation of embedded pathogens.

Supercritical CO₂ for terminal sterilization began with the idea that SCCO₂ has certain disinfection properties. NovaSterilis has expanded and optimized the technology, producing a viable terminal sterilization process that is protected by several patents.  The NovaSterilis SCCO₂ process strives to achieve and total inactivation of microbes including bacterial endospores.  When the potency of the NovaSterilis process is coupled with the environmentally benign nature of carbon dioxide, the results show a very effective approach to sterilizing medical grade products; many of which previously could not be sterilized because of their delicate nature using conventional means.

At NovaSterilis, we welcome all inquiries and are open to exploring new applications for our SCCO₂ sterilization technology.  Please use the contact information on this site for questions or potential collaborations.